"Of all the frictional resistance, the one that most retards human movement is ignorance, what Buddha called "the greatest evil in the world." The friction which results from ignorance can be reduced only by the spread of knowledge and the unification of the heterogeneous elements of humanity. No effort could be better spent." [Nikola Tesla]
Ignorance is a mental state lacking full knowledge or awareness. One can be intelligent yet lack awareness on any given topic. Ignorance can be cured by study with an open mind. A closed or made-up mind, then, preserves ignorance. Belief systems, composed of beliefs, opinions, dogma and doctrine, are all fixed knowledge and not open to more awareness and expanded knowledge.
Examples of locked-in Belief Systems are religion, political correctness, traditions, habits, dogmatic (peer reviewed) science, political party platforms, 'modern' school curricula, political correctness, unquestioning obedience to unelected authority, rigid rules and regulations, job descriptions, rule sets, etc.
"Men are fighting... because they are convinced that the extermination of adversaries is the only means of promoting their own well-being." [Ludwig von Mises]
Rosicrucian Order AMORC
"More than ever, it is time now for us to move from religiosity to spirituality, which means replacing the sole belief in God with the knowledge of divine laws - that is, universal, natural, and spiritual laws. The well-being we seek, including on a material plane, is to be found in this knowledge and in the wisdom that ensues. An ancient Rosicrucian adage says, It is from ignorance and ignorance alone that humans must free themselves. It is indeed at the origin of the worst things a person can do to oneself, to others, and to one's environment. It is also the source of different superstitions that demean humanity and prevent it from finding complete fulfillment. So give a spiritual direction to your life. In other words, do not be just a living thing, be a living soul." [Manifesto Appellatio, Rosicrucian Order AMORC]